Article

Ruscogenin Alleviates Intestinal Bleeding and Blood Flow Induced by Dasatinib through ROCK/MLC Pathway

2020-10-26

Abstract excerpt

<title>Abstract</title> <p>BackgroundAs a second-generation broad-spectrum tyrosine kinase inhibitor, Dasatinib has the antitumor effect of inhibiting tyrosine kinases such as BCR-ABL and SRC. It is mainly used to treat chronic and acute patients with chronic myelogenous leukemia. However, Dasatinib has many side effects, including gastrointestinal bleeding, respiratory infections, and renal failure, and effectiv...

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Literature Corpus work: cd974eab-1c91-590c-99c3-184356c271f4
DOI: 10.21203/rs.3.rs-96134/v1

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