Article

A potential hepatoprotective effect of ranolazine against methotrexate-induced liver injury in rats

2023-05-24

Abstract excerpt

Methotrexate (MTX) is an important drug for rheumatic and non-rheumatic disease therapy. MTX has been associated with many adverse effects ranging from asymptomatic transaminase elevation to fibrotic tissue formation and fatal hepatic necrosis due to oxidative stress. Concerns regarding potential liver toxicity have led to the avoidance of medication, termination, or advice for inquiries in clinical care. The prot...

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Literature Corpus work: cd66f523-6601-5f51-83bc-5cda2998b723
DOI: 10.22541/au.168490817.77526721/v1

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