Article

Visualizing Antineoplastic Activity with a Whole Organism Drosophila melanogaster Screen

2021-09-01

Abstract excerpt

Cancer is a disease characterized by high mitosis rates with a loss of regulation. Many antineoplastics, those drugs used to treat cancer, act by slowing or halting mitosis. We are developing a whole-organism screening protocol to identify novel antineoplastics. After exposing Drosophila melanogaster eggs and larva to a compound, their growth rate and population decrease if mitosis inhibition or arrest occur. We s...

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Literature Corpus work: cd65226f-66dc-5549-8240-bf0ee567d870
DOI: 10.1101/2021.09.01.458511

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