Article

Insulin Predicts Methotrexate Response by Affecting Transcription of Methotrexate Target Genes in the Treatment-Naive Rheumatoid Arthritis

2025-05-20

Abstract excerpt

Methotrexate (MTX), the most common first-line treatment in rheumatoid arthritis, is often insufficient with no model capable of predicting response. The RA classification criteria including information about DAS44, autoantibodies and inflammation were applied to 257 patients with newly diagnosed inflammatory arthritis. 172 received MTX as the first anti-rheumatic drug and response was recorded at 1 year follow-up...

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Literature Corpus work: cd4e73d6-5dc7-57a0-abac-4750073bb43f
DOI: 10.20944/preprints202505.1532.v1

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