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Article

Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis.

Annals of the rheumatic diseases - 1 Sept 2012

Bulatovic Maja, Heijstek Marloes W, Van Dijkhuizen E H Pieter, Wulffraat Nico M, Pluijm Saskia M F, de Jonge Robert

Abstract excerpt

OBJECTIVES: Methotrexate (MTX) is a cheap and efficacious drug in juvenile idiopathic arthritis (JIA) treatment. If JIA patients are unresponsive to MTX, early and effective combination treatment with biologicals is required to prevent joint damage. The authors developed a prediction model to identify JIA patients not responding to MTX. METHODS: In a cohort of 183 JIA patients, clinical variables and single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22473625
DOI: 10.1136/annrheumdis-2011-200942

Genes

ABCB1
ABCC1

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