Article

Age-dependent RGS5 loss in pericytes induces cardiac dysfunction and fibrosis in the heart

2023-12-08

Abstract excerpt

<h4>Background</h4> Pericytes are capillary-associated mural cells involved in the maintenance and stability of the vascular network. Although ageing is one of the main risk factors for cardiovascular disease, the consequences of ageing on cardiac pericytes are unknown. <h4>Methods</h4> In this study, we have combined single-nucleus RNA sequencing and histological analysis to determine the effects of ageing on c...

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Literature Corpus work: cd3b7c7f-56b1-5a35-9985-3e2a859eaf63
DOI: 10.1101/2023.12.08.570774

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