Article
Cellular Targets of the HIV-1 Protease: Just the Tip of the Iceberg?
2023-02-03
Abstract excerpt
The human immunodeficiency virus 1 (HIV-1) viral protease (PR) is one of the most studied viral enzymes, and approval of drugs targeting its catalytic activity opened the door to the develop-ment of highly active antiretroviral therapy (HAART). Despite the fact that its crucial role in viri-on maturation is well characterized, an increasing body of research is starting to focus on its abil-ity to cleave host cell...
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Identifiers and source
- Literature Corpus work
- cccddf62-9a08-58fc-981d-770b695b4be5
- DOI
- 10.20944/preprints202302.0058.v1
