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Identification of known and novel germ cell cancer‐specific (embryonic) miRs in serum by high‐throughput profiling

7 Nov 2014

Abstract excerpt

microRNAs (miRs) are short non-coding RNA molecules (≈21 nucleotides) involved in regulation of translation. As such they are crucial for normal cell development and differentiation as well as cellular maintenance. Dysregulation of miRs has been reported in various diseases, including cancer. Interestingly, miRs can be informative as tumor classifiers and disease biomarkers. Recent studies demonstrated the...

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PMID: 25382245
DOI: 10.1111/andr.298

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