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Trans-NanoSim characterizes and simulates nanopore RNA-seq data

2019-10-10

Abstract excerpt

We introduce Trans-NanoSim, the first tool that simulates reads with technical and transcriptome-specific features learnt from nanopore RNA-seq data. Through benchmarking on sets of nanopore reads from human and mouse reference transcriptomes, we show the robustness of Trans-NanoSim in capturing the characteristics of nanopore cDNA and direct RNA reads. As a cost-effective alternative to sequencing real transcript...

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Literature Corpus work
cc4b8596-dfe4-5839-b3eb-db28c6c4d1f3
DOI
10.1101/800110
Open publication

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Trans-NanoSim characterizes and simulates nanopore RNA-seq dataDOI 10.1101/800110
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