Article

Novel microRNA-455-3p mouse models to study Alzheimer’s disease pathogenesis

2021-09-24

Abstract excerpt

MicroRNA-455-3p is one of the highly conserved miRNAs involved in several human diseases but newly explored by our lab in Alzheimer’s disease (AD). Our past studies unveiled the biomarker and therapeutic potentials of miR-455-3p in AD. Our in vitro study exhibited the protective role of miR-455-3p against AD toxicities in reducing full-length APP and amyloid-β (Aβ) protein levels, and also reducing defective mito...

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Literature Corpus work: 51077c47-58f5-5625-93cc-70167733d591
DOI: 10.1101/2021.09.23.461513

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