Article

IgStrand: A universal residue numbering scheme for the Immunoglobulin-fold (Ig-fold) to study Ig-Proteomes and Ig-Interactomes

2024-06-11

Abstract excerpt

<h4>ABSTRACT</h4> The Immunoglobulin fold (Ig-fold) is found in proteins from all domains of life and represents the most populous fold in the human genome, with current estimates ranging from 2 to 3% of protein coding regions. That proportion is much higher in the surfaceome where Ig and Ig-like domains orchestrate cell-cell recognition, adhesion and signaling. The ability of Ig-domains to reliably fold and self...

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Literature Corpus work: cbe1c930-57bf-5d3f-892a-c859552b23ab
DOI: 10.1101/2024.06.10.598201

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