Article

Topological and Structural Plasticity of the single Ig fold and the double Ig fold present in CD19

2021-06-05

Abstract excerpt

<h4>ABSTRACT</h4> The Ig-fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig-fold is not just the elementary structural domain of antibodies and TCRs, it is also at the heart of a staggering 30% of immunologic cell surface receptors, making it a major orchestrator of cell-cell-interactions. While BCRs, TCRs, and numerous Ig-based cell surface receptors form...

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Literature Corpus work: 9c628611-1a51-54e8-8360-78318dec8ff8
DOI: 10.1101/2021.06.04.447059

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