Article

Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolution

2023-03-02

Abstract excerpt

<title>Abstract</title> <p>During the COVID-19 pandemic, human behavior change as a result of nonpharmaceutical interventions such as isolation may have induced directional selection for viral evolution. By combining previously published empirical clinical data analysis and multi-level mathematical modeling, we found that the SARS-CoV-2 variants selected for as the virus evolved from the pre-Alpha to the Delta va...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cbc4926a-c2fe-56dd-a2c7-cdd188a30591
DOI: 10.21203/rs.3.rs-2619513/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolutionDOI 10.21203/rs.3.rs-2619513/v1Read

Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolutionSemantic proximity Read

Controlling long-term SARS-CoV-2 infections can slow viral evolution and reduce the risk of treatment failure.Semantic proximity Read

Phenotypic evolution of SARS-CoV-2: a statistical inference approach.Semantic proximity Read

Investigating the evolutionary origins of the first three SARS-CoV-2 variants of concernSemantic proximity Read

Endemic means change as SARS-CoV-2 evolvesSemantic proximity Read

Community level variability in Bronx COVID-19 hospitalizations associated with differing viral variant adaptive strategies during the second year of the pandemicSemantic proximity Read

Impacts of vaccination on the variant selection of SARS-CoV-2 and the subsequent case hospitalization rate: insights from the first U.S. Omicron waveSemantic proximity Read

Within-host evolution of SARS-CoV-2: how often are <i>de novo</i> mutations transmitted?Semantic proximity Read

Understanding patterns of variant emergence and spread in an ongoing epidemicSemantic proximity Read

Possible future waves of SARS-CoV-2 infection generated by variants of concern with a range of characteristicsSemantic proximity Read

Combined Effects of Severe Immunocompromise and Prolonged Virus Shedding on Within-Host SARS-CoV-2 Evolution in COVID-19Semantic proximity Read

Possible future waves of SARS-CoV-2 infection generated by variants of concern with a range of characteristics.Semantic proximity Read