Article

The Vagus Nerve Mediates the Physiological but not Pharmacological Effects of PYY <sub>3-36</sub> on Food Intake

2020-08-07

Abstract excerpt

Peptide YY (PYY 3-36 ) is a post-prandially released gut hormone with potent appetite-reducing activity mediated by the neuropeptide Y (NPY) Y2 receptor (Y2R). However, the neuronal pathways by which PYY 3-36 acts to supress appetite are unclear. Determining how the PYY 3-36 system physiologically regulates food intake may help exploit its therapeutic potential. Here we demonstrate that germline and post-natal...

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Literature Corpus work: cb91ae9f-76df-551a-9241-b5fd28f454f4
DOI: 10.1101/2020.08.07.241851

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