Article

An endogenous retroviral element co-opts an upstream regulatory sequence to achieve somatic expression and mobility

2025-01-02

Abstract excerpt

Retrotransposons, multi-copy sequences that propagate via copy-and-paste mechanisms involving an RNA intermediate, occupy large portions of all eukaryotic genomes. A great majority of their manifold copies remain silenced in somatic cells, nevertheless, some are transcribed, often in a tissue specific manner, and a small fraction retains its ability to mobilize. Retrotransposon expression or mobility are increasi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb45e575-9a09-503c-98c3-d42f330edcdd
DOI: 10.1101/2025.01.02.631056

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An endogenous retroviral element co-opts an upstream regulatory sequence to achieve somatic expression and mobilityDOI 10.1101/2025.01.02.631056Read

Lifestyles of <i>Gypsy</i> -family transposons shape their regulatory mechanismsSemantic proximity Read

Expression of retrotransposons contributes to aging in <i>Drosophila</i>Semantic proximity Read

Retrotransposon life cycle and its impacts on cellular responsesSemantic proximity Read

Somatic transposition in the <i>Drosophila</i> intestine occurs in active chromatin and is associated with tumor suppressor gene inactivationSemantic proximity Read

LINES between species: Evolutionary dynamics of LINE-1 retrotransposons across the eukaryotic tree of lifeSemantic proximity Read

The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes.Semantic proximity Read

Functional Adaptations of Endogenous Retroviruses to the <i>Drosophila</i> Host Underlie their Evolutionary DiversificationSemantic proximity Read

Identification and characterization of retro-DNAs, a new type of retrotransposons originated from DNA transposons, in primate genomesSemantic proximity Read

Active human retrotransposons: variation and disease.Semantic proximity Read

Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem CellsSemantic proximity Read

Comparative Genomics Reveals LINE-1 Recombination with Diverse RNAsSemantic proximity Read

The diverse evolutionary histories of domesticated metaviral capsid genes in mammalsSemantic proximity Read