Article

Modulation of motor cortical theta and gamma oscillations using phase-targeted, closed-loop optogenetic stimulation of local excitatory and inhibitory neurons

2025-08-22

Abstract excerpt

Theta and gamma oscillations are prominent features of cortical local field potentials (LFPs) and stimulation of the motor cortex at these frequencies can enhance motor learning. Phase-targeted closed-loop stimulation could provide a more precise and effective method to modulate these oscillations, particularly if stimulation parameters could harness the dynamics of the specific circuit mechanisms underpinning the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb4444f7-0895-5462-8ee3-3bf0a43ac013
DOI: 10.1101/2025.08.21.670039

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Modulation of motor cortical theta and gamma oscillations using phase-targeted, closed-loop optogenetic stimulation of local excitatory and inhibitory neuronsDOI 10.1101/2025.08.21.670039Read

Manipulating single-unit theta phase-locking with PhaSER: An open-source tool for real-time phase estimation and manipulationSemantic proximity Read

Closed-loop optogenetic control of normal and pathological network dynamicsSemantic proximity Read

Thalamic feedback shapes brain responses evoked by cortical stimulation in mice and humansSemantic proximity Read

Predicting and phase targeting brain oscillations in real-timeSemantic proximity Read

All-optical electrophysiology reveals behavior-dependent dynamics of excitation and inhibition in the hippocampusSemantic proximity Read

Excitatory-inhibitory windows shape coherent neuronal dynamics driven by optogenetic stimulation in the primate brainSemantic proximity Read

Theta-burst stimulation entrains frequency-specific oscillatory responsesSemantic proximity Read

Distinct laminar origins of high-gamma and low-frequency ECoG signals revealed by optogeneticsSemantic proximity Read

Frequency Mismatch Critically Limits Gamma Entrainment: A Kuramoto Model Study Supporting Personalized GENUS TherapySemantic proximity Read

Phase-dependent closed-loop intersectional short-pulse stimulation reduces seizure duration: From computational modeling to clinical applicationSemantic proximity Read

Spatially specific, closed-loop infrared thalamocortical deep brain stimulationSemantic proximity Read

Cortical rhythms are modulated by respirationSemantic proximity Read