Article

Phase-dependent closed-loop intersectional short-pulse stimulation reduces seizure duration: From computational modeling to clinical application

2026-08-23

Abstract excerpt

Drug-resistant epilepsy affects one-third of patients with persistent seizures despite optimal therapy. Intersectional short-pulse (ISP) stimulation is a novel transcranial electrical stimulation technique designed to deliver temporally precise, spatially targeted modulation of pathological brain activity. Here, we combined computational modeling with measurements in a rat epilepsy model and in patients with epile...

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Literature Corpus work: c1fc2be1-7b44-5346-88b9-1136615bcffb
DOI: 10.64898/2026.08.19.745828

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Phase-dependent closed-loop intersectional short-pulse stimulation reduces seizure duration: From computational modeling to clinical applicationDOI 10.64898/2026.08.19.745828Read

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