Article

Comprehensive antibiotic-linked mutation assessment by Resistance Mutation Sequencing (RM-seq)

2018-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Acquired mutations are a major mechanism of bacterial antibiotic resistance generation and dissemination, and can arise during treatment of infections. Early detection of sub-populations of resistant bacteria harbouring defined resistance mutations could prevent inappropriate antibiotic prescription. Here we present RM-seq, a new amplicon-based DNA sequencing workflow based on single molecule ba...

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Literature Corpus work: cb4089f2-a5ac-5321-852a-9926b5ab2376
DOI: 10.1101/257915

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