Article

Development and application of genetic ancestry reconstruction methods to study diversity of patient-derived models in the NCI PDXNet Consortium

2022-10-25

Abstract excerpt

Personalized medicine holds great promise for improving cancer outcomes, yet there is a large inequity in the demographics of patients from whom genomic data and models, including patient derived xenografts (PDX), are developed and for whom treatments are optimized. In this study we develop a genetic ancestry pipeline for the Cancer Genomics Cloud, which we use to assess the diversity of models currently available...

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Literature Corpus work: cb3a16df-6273-5505-b417-ca6bb47a05e5
DOI: 10.1101/2022.10.24.513591

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