Article

Single-cell RNA-sequencing implicates venous endothelial cells as a source of VEGF-A-mediated neo-angiogenesis in neuroinflammation

2022-11-15

Abstract excerpt

<h4>ABSTRACT</h4> Histopathological studies of multiple sclerosis (MS), a demyelinating disease of the central nervous system (CNS), and its animal model, experimental autoimmune encephalomyelitis (EAE), have found newly formed leaky vessels in demyelinated acute and chronic plaques, in addition to blood-brain barrier (BBB) damage in existing vessels, that exacerbate disease pathology by increasing infiltration o...

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Literature Corpus work: cb2e4f6f-b407-53db-819d-77efe9a9725b
DOI: 10.1101/2022.11.15.516660

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