Article

G9a/GLP inhibitor UNC0642 induces growth arrest in colorectal cancer via induction of ROS generation, coordinated overexpression of GADD genes, and the JNK/p38 MAPK pathway

2024-06-20

Abstract excerpt

<title>Abstract</title> <p>Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer death worldwide. Hence, new therapeutic agents are urgently needed to manage colorectal cancer effectively. The epigenetic abnormalities of chromatin drive the initiation and progression of human cancers. Therefore, DNA methyltransferase and histone deacetylase inhibitors have been develop...

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Literature Corpus work: cb278839-40f6-5391-b92e-23ea4561a332
DOI: 10.21203/rs.3.rs-4532655/v1

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G9a/GLP inhibitor UNC0642 induces growth arrest in colorectal cancer via induction of ROS generation, coordinated overexpression of GADD genes, and the JNK/p38 MAPK pathwayDOI 10.21203/rs.3.rs-4532655/v1Read

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