Article

Small RNAs are trafficked from the epididymis to developing mammalian sperm

2017-09-27

Abstract excerpt

<h4>Summary</h4> RNAs present in mature mammalian sperm are delivered to the zygote at fertilization, where they have the potential to affect early development. The biogenesis of the small RNA payload of mature sperm is therefore of great interest, as it may be a target of signaling pathways linking paternal conditions to offspring phenotype. Recent studies have suggested the surprising hypothesis that the small...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb0e3b77-8902-5a2f-bb9f-6d7570c6bd47
DOI: 10.1101/194522

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Small RNAs are trafficked from the epididymis to developing mammalian spermDOI 10.1101/194522Read

Epididymal acquired sperm microRNAs modify post-fertilization embryonic gene expressionSemantic proximity Read

Epididymal acquired sperm microRNAs modify post-fertilization embryonic gene expressionSemantic proximity Read

Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenomeSemantic proximity Read

Small RNAs Gained during Epididymal Transit of Sperm Are Essential for Embryonic Development in MiceSemantic proximity Read

Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic InformationSemantic proximity Read

Profiling of epididymal small non‐protein‐coding RNA sSemantic proximity Read

The repertoire of testicular extracellular vesicles cargoes and their involvement in inter-compartmental communication required for spermatogenesisSemantic proximity Read

Small RNAs, spermatogenesis, and male infertility: a decade of retrospectSemantic proximity Read

All you need to know about sperm RNAsSemantic proximity Read

The MicroRNA Signature of Mouse Spermatozoa Is Substantially Modified During Epididymal Maturation1Semantic proximity Read

Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAsSemantic proximity Read

Epididymal RNase T2 contributes to astheno-teratozoospermia and intergenerational metabolic disorder through epididymosome-sperm interactionSemantic proximity Read