Article

Fitness, Physical Activity, and Cardiovascular Disease: Longitudinal and Genetic Analyses in the UK Biobank Study

2017-05-12

Abstract excerpt

<h4>Background</h4> Exercise is inversely related with cardiovascular disease (CVD), but large-scale studies of incident CVD events are lacking. Moreover, little is known about genetic determinants of fitness and physical activity, and modifiable effects of exercise in individuals with elevated genetic risk of CVD. Finally, causal analyses of exercise traits are limited. <h4>Methods</h4> We estimated association...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb027d22-fb27-5f6b-a8f1-775e95b950c7
DOI: 10.1101/136192

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Fitness, Physical Activity, and Cardiovascular Disease: Longitudinal and Genetic Analyses in the UK Biobank StudyDOI 10.1101/136192Read

Assessment of causal associations between handgrip strength and cardiovascular diseases: A two sample mendelian randomization studySemantic proximity Read

Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK BiobankSemantic proximity Read

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.Semantic proximity Read

Aerobic Fitness and Health-Related Phenotypes: A Two-Stage Phenome-Wide Mendelian Randomization Study.Semantic proximity Read

Cardiorespiratory Fitness, Genetic Risk, and Incident Atherosclerotic Cardiovascular Events: A Prospective Cohort Study.Semantic proximity Read

Biological Insights Into Muscular Strength: Genetic Findings in the UK BiobankSemantic proximity Read

Genome-wide polygenic risk score for muscle strength predicts lower risk for common diseases and longer life span among the Finnish population: a prospective population based cohort study of the 342 443 FinnGen participantsSemantic proximity Read

Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT StudySemantic proximity Read

Genome-wide association study of habitual physical activity in over 277,000 UK Biobank participants identifies multiple variants including <i>CADM2</i> and <i>APOE</i>Semantic proximity Read

A Whole-Genome Approach Discovers Novel Genetic and Non-Genetic Variance Components Modulated by Lifestyle for Cardiovascular HealthSemantic proximity Read

Genetic Liability to Higher Muscle Strength Associates with a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Physical Activity in Adulthood: A Longitudinal Cohort StudySemantic proximity Read

Joint and interactive associations of body mass index and genetic factors with cardiovascular disease: a prospective study in UK Biobank.Semantic proximity Read