Article
Antibody feedback regulation of memory B cell development in SARS-CoV-2 mRNA vaccination
2022-08-10
Abstract excerpt
Feedback inhibition of humoral immunity by antibodies was initially documented in guinea pigs by Theobald Smith in 1909, who showed that passive administration of excess anti-Diphtheria toxin inhibited immune responses 1 . Subsequent work documented that antibodies can enhance or inhibit immune responses depending on antibody isotype, affinity, the physical nature of the antigen, and engagement of immunoglobulin (...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- cab7dfc0-bcce-5212-ba5b-04f42e7a9082
- DOI
- 10.1101/2022.08.05.22278483
