Article
Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases
2022-02-10
Abstract excerpt
Aging is a major risk factor for most diseases. Pathways regulating metabolism, including nutrient sensing, energy production, and synthesis and degradation of macromolecules, have been identified as key regulators of organismal lifespan and implicated in several late-onset diseases, such as most neurodegenerative disorders. In this review, we focus on emerging evidence that links the remodeling of key organelles,...
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Identifiers and source
- Literature Corpus work
- ca9f579a-db36-5d8d-817e-1179c1a25a3f
- DOI
- 10.1016/j.coisb.2022.100416