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Mitophagy in aging and longevity

10 Dec 2021

Abstract excerpt

The clearance of damaged or unwanted mitochondria by autophagy (also known as mitophagy) is a mitochondrial quality control mechanism postulated to play an essential role in cellular homeostasis, metabolism, and development and confers protection against a wide range of diseases. Proper removal of damaged or unwanted mitochondria is essential for organismal health. Defects in mitophagy are associated with...

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PMID: 34889504
DOI: 10.1002/iub.2585

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