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Mitochondria in aging and age-associated diseases

27 Feb 2025

Abstract excerpt

Mitochondria, essential for cellular energy, are crucial in neurodegenerative disorders (NDDs) and their age-related progression. This review highlights mitochondrial dynamics, mitovesicles, homeostasis, and organelle communication. We examine mitochondrial impacts from aging and NDDs, focusing on protein aggregation and dysfunction. Prospective therapeutic approaches include enhancing mitophagy, improving...

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PMID: 40023438
DOI: 10.1016/j.mito.2025.102022

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