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The crucial impact of lysosomes in aging and longevity

29 Apr 2016

Abstract excerpt

Lysosomes are the main catabolic organelles of a cell and play a pivotal role in a plethora of cellular processes, including responses to nutrient availability and composition, stress resistance, programmed cell death, plasma membrane repair, development, and cell differentiation. In line with this pleiotropic importance for cellular and organismal life and death, lysosomal dysfunction is associated with many...

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PMID: 27125853
DOI: 10.1016/j.arr.2016.04.009

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