Time-varying effects are common in genetic control of gestational duration

Abstract excerpt

Preterm birth is a major burden to neonatal health worldwide, determined in part by genetics. Recently, studies discovered several genes associated with this trait or its continuous equivalent – gestational duration. However, their effect timing, and thus clinical importance, is still unclear. Here, we use genotyping data of 31,000 births from the Norwegian Mother, Father and Child cohort (MoBa) to investigate dif...

Topics

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• Child
• Genome-Wide Association Study
• Gestational Age
• Infant, Newborn
• Mothers
• Phenotype
• Pregnancy
• Premature Birth

Identifiers and source

Literature Corpus work

ca86b5ea-c1fd-5436-ac6f-5edf8a2e0853

DOI

10.1101/2023.02.07.23285609