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Article

Time-Variant Genetic Effects as a Cause for Preterm Birth: Insights from a Population of Maternal Cousins in Sweden.

G3 (Bethesda, Md.) - 3 Apr 2017

Juodakis Julius, Bacelis Jonas, Zhang Ge, Muglia Louis J, Jacobsson Bo

Abstract excerpt

Preterm delivery (PTD) is the leading cause of neonatal mortality worldwide, yet its etiology remains largely unexplained. We propose that the genetic factors controlling this trait could act in a nonuniform manner during pregnancy, with each factor having a unique "window of sensitivity." We test this hypothesis by modeling the distribution of gestational ages (GAs) observed in maternal cousins from the Swedish...

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Identifiers

PMID: 28250013
DOI: 10.1534/g3.116.038612
PMCID: PMC5386882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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