Article
Time-varying effects are common in genetic control of gestational duration.
Human molecular genetics - 4 Jul 2023
Juodakis Julius, Ytterberg Karin, Flatley Christopher, Sole-Navais Pol, Jacobsson Bo
Abstract excerpt
Preterm birth is a major burden to neonatal health worldwide, determined in part by genetics. Recently, studies discovered several genes associated with this trait or its continuous equivalent-gestational duration. However, their effect timing, and thus clinical importance, is still unclear. Here, we use genotyping data of 31 000 births from the Norwegian Mother, Father and Child cohort (MoBa) to investigate...
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