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Disulfidptosis-related gene expression reflects the prognosis of drug-resistant cancer patients and inhibition of MYH9 reverses sorafenib resistance

14 Aug 2024

Abstract excerpt

• Disulfidptosis-related genes are significantly associated with somatic alteration patterns, immune infiltration, prognosis, and drug sensitivity in various tumors. • Disulfidptosis-related genes are associated with drug sensitivity to various drugs, and MYH9, a disulfidptosis-related gene, plays a vital role in sorafenib resistance in hepatocellular carcinoma. • Inhibiting the expression of MYH9 to a certain...

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PMID: 39146597
DOI: 10.1016/j.tranon.2024.102091

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