Article

An EBNA1-YAP signaling axis drives immune escape through CD276 in EBV-associated gastric cancer

2024-01-19

Abstract excerpt

<title>Abstract</title> <p>Clinical efficacy of anti-PD1 immunotherapy is often with low response rates in Epstein-Barr virus-associated gastric cancer (EBVaGC). To gain insights into the immune escape and discovering the key molecule against anti-tumor immunity, we performed an immune checkpoint screening with transcriptome profiling and IHC staining data. CD276 was found as an independent immune suppressive mol...

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Literature Corpus work: ca2b2091-8359-58c3-80ef-096c88a1cb12
DOI: 10.21203/rs.3.rs-3283256/v1

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