Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms

21 Jan 2021

Abstract excerpt

Epstein-Barr virus-positive gastric cancer [EBV (+) GC] is a distinct GC subtype with unique genetic and epigenetic aberrations. Here, we examined resected GC samples and publicly available microarray data and The Cancer Genome Atlas (TCGA) database to identify the mechanism underlying overexpression of PD-L1 in EBV (+) GC. We found that high levels of PD-L1 overexpression in EBV (+) GC were caused by focal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33479394
DOI: 10.1038/s41598-021-81667-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanismsPMID 33479394Read ↗

Genetic landscape and PD-L1 expression in Epstein–Barr virus-associated gastric cancer according to the histological patternSemantic proximity Read ↗

Tumor-Infiltrating T Cells in EBV-Associated Gastric Carcinomas Exhibit High Levels of Multiple Markers of Activation, Effector Gene Expression, and ExhaustionSemantic proximity Read ↗

Differences in the Tumor Microenvironment of EBV-Associated Gastric Cancers Revealed Using Single-Cell Transcriptome AnalysisSemantic proximity Read ↗

Epstein-Barr virus-associated gastric cancer: disease that requires special approach.Semantic proximity Read ↗

Overview of Epstein–Barr-Virus-Associated Gastric Cancer Correlated with Prognostic Classification and Development of Therapeutic OptionsSemantic proximity Read ↗

An EBNA1-YAP signaling axis drives immune escape through CD276 in EBV-associated gastric cancerSemantic proximity Read ↗

Molecular Features and Translational Outlook for Epstein–Barr virus-associated Gastric CancerSemantic proximity Read ↗

High PD-L1 expression in gastric cancer (GC) patients and correlation with molecular featuresSemantic proximity Read ↗

Profiles of PD-1, PD-L1, PD-L2 in Gastric Cancer and Their Relation with Mutation, Immune Infiltration, and Survival.Semantic proximity Read ↗

Classification of gastric cancer by EBV status combined with molecular profiling predicts patient prognosisSemantic proximity Read ↗

Functional loss of ARID1A is tightly associated with high PD‐L1 expression in gastric cancerSemantic proximity Read ↗

Epstein-Barr virus-positive gastric cancer: a distinct molecular subtype of the disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.