Article

Prototype-based continual cell-type annotation reveals cellular state transitions in expanding single-cell atlases

2026-03-08

Abstract excerpt

<h4>ABSTRACT</h4> Large-scale single-cell atlases provide an increasingly comprehensive view of cellular diversity, but their continued expansion across studies poses a fundamental challenge: preserving consistent cell identities while capturing biological variation in cellular states. Most existing annotation frameworks are built around static references, making it difficult to incorporate newly generated datase...

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Literature Corpus work: c9ecf53c-321f-5f30-b441-0bf9355c0256
DOI: 10.64898/2026.03.05.709973

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