Article

A generic pipeline for CADD Score generation: chickenCADD and turkeyCADD

2024-11-03

Abstract excerpt

Combined Annotation Dependent Depletion (CADD) is a machine learning approach used to predict the deleteriousness of genetic variants across a genome. By integrating diverse genomic features, CADD assigns a PHRED-like rank score to each potential variant. Unlike other methods, CADD does not rely on limited datasets of known pathogenic or benign variants but uses larger and less biased training sets. The rapid incr...

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Literature Corpus work: c997d49a-9576-593f-9d59-b59ad7443bc0
DOI: 10.1101/2024.11.01.621569

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