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Article

DANN: a deep learning approach for annotating the pathogenicity of genetic variants.

Bioinformatics (Oxford, England) - 1 Mar 2015

Quang Daniel, Chen Yifei, Xie Xiaohui

Abstract excerpt

UNLABELLED: Annotating genetic variants, especially non-coding variants, for the purpose of identifying pathogenic variants remains a challenge. Combined annotation-dependent depletion (CADD) is an algorithm designed to annotate both coding and non-coding variants, and has been shown to outperform other annotation algorithms. CADD trains a linear kernel support vector machine (SVM) to differentiate evolutionarily...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25338716
DOI: 10.1093/bioinformatics/btu703
PMCID: PMC4341060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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