Article

Notch signaling functions in non-canonical juxtacrine manner in platelets to amplify thrombogenicity

2022-05-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Notch signaling is an evolutionarily conserved pathway that dictates cell fate decisions in mammalian cells including megakaryocytes. Existence of functional Notch signaling in enucleate platelets that are generated as cytoplasmic buds from megakaryocytes still remains elusive. <h4>Methods</h4> Platelets were isolated from human blood by differential centrifugation under in...

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Literature Corpus work: 4ef97bdc-c335-5948-b251-14e51a603205
DOI: 10.1101/2022.05.06.490944

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