Article

N-terminal VP1 truncations favor <i>T</i> =1 norovirus-like particles

2020-11-26

Abstract excerpt

Noroviruses cause immense sporadic gastroenteritis outbreaks worldwide. Emerging genotypes, which are divided based on VP1 sequence, further enhance this public threat. Self-assembling properties of the human norovirus major capsid protein VP1 are crucial for using virus-like particles (VLPs) for vaccine development. However, there is no vaccine available yet. Here, VLPs from different variants produced in insect...

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Identifiers and source

Literature Corpus work: c91206ff-e506-5ed0-84be-0451dc465349
DOI: 10.1101/2020.11.25.396499

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