Article

ZFP36 as a Key Regulator of CD4+ T Cell Subset Balance in Immune Checkpoint Inhibitor-Induced Adverse Events in Lung Adenocarcinoma

2025-09-23

Abstract excerpt

<title>Abstract</title> <bold>Background:</bold> Immune checkpoint inhibitors (ICIs) have revolutionized lung adenocarcinoma (LUAD) treatment but are frequently accompanied by immune-related adverse events (irAEs). The zinc finger protein 36 (ZFP36), also known as tristetraprolin, serves as a critical post-transcriptional regulator of mRNA stability and has emerged as a key modulator of T cell function. How...

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Literature Corpus work: c9057c88-5f9c-50e8-9cd4-c971c61cb203
DOI: 10.21203/rs.3.rs-7339858/v1

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