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Article

Comprehensive analysis of programmed cell death and oridonin target identification in primary lung cancer for prognostic prediction and therapeutic strategies.

Scientific reports - 3 Apr 2026

Xiang Xiaoqin, Yu Xiang, Li Jing, Cao Wei, Miao Rongrong, Zhao Xin

Abstract excerpt

This study investigated the involvement of Oridonin-related prognostic genes in programmed cell death (PCD) in primary lung cancer and constructed a corresponding prognostic model. Transcriptomic, mutation, and clinical data from the TCGA database, including the TCGA-LUSC (Lung Squamous Cell Carcinoma) and TCGA-LUAD (Lung Adenocarcinoma) cohorts with 989 primary lung cancer samples, were analyzed. A total of 38...

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Identifiers

PMID: 41933146
DOI: 10.1038/s41598-026-47184-4
PMCID: PMC13199421

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FLNC
FOSL1

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