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Article

Role of PRDM1 in Tumor Immunity and Drug Response: A Pan-Cancer Analysis

15 Dec 2020

Abstract excerpt

Background: PR domain zinc finger protein 1 (PRDM1) is a regulator of both B cell and T cell differentiation and plays a critical role in immunosuppression. Its role in tumor immunity and correlation with drug response remain unknown. Methods: This work comprehensively analyzed the transcriptional expression pattern of the PRDM1 among 33 types of malignancies from The Cancer Genome Atlas and the Genotype-Tissue...

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PMID: 33384601
DOI: 10.3389/fphar.2020.593195

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