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Article

Pathogen to commensal: longitudinal within-host population dynamics, evolution, and adaptation during a chronic >16-year <i>Burkholderia pseudomallei</i> infection

2019-02-17

Abstract excerpt

Although acute melioidosis is the most common outcome of Burkholderia pseudomallei infection, we have documented a case, P314, where the disease severity lessened with time, and the pathogen evolved towards a commensal relationship with the host. In the current study, we used whole-genome sequencing to monitor this chronic infection to better understand B. pseudomallei persistence in P314’s sputum despite intens...

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Literature Corpus work
c8836af9-fe2d-5769-aae7-5d127f23ff6e
DOI
10.1101/552109
Open publication

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Pathogen to commensal: longitudinal within-host population dynamics, evolution, and adaptation during a chronic >16-year <i>Burkholderia pseudomallei</i> infectionDOI 10.1101/552109
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