Article

Association of Structural Variation with Cardiometabolic Traits in Finns

2020-12-13

Abstract excerpt

The contribution of genome structural variation (SV) to quantitative traits associated with cardiometabolic diseases remains largely unknown. Here, we present the results of a study examining genetic association between SVs and cardiometabolic traits in the Finnish population. We used sensitive methods to identify and genotype 129,166 high-confidence SVs from deep whole genome sequencing (WGS) data of 4,848 indivi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c86f5a17-2b4b-5c02-b4f3-b31226de8296
DOI: 10.1101/2020.12.13.422502

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Association of Structural Variation with Cardiometabolic Traits in FinnsDOI 10.1101/2020.12.13.422502Read

Association of structural variation with cardiometabolic traits in Finns.Semantic proximity Read

Modeling structural variations sequencing information to address missing heritability and enhance risk predictionSemantic proximity Read

Structural variants contribute substantially to complex trait heritabilitySemantic proximity Read

Structural variants contribute substantially to complex trait heritabilitySemantic proximity Read

Genome-wide rare variant analysis for thousands of phenotypes in 54,000 exomesSemantic proximity Read

Exome sequencing identifies high-impact trait-associated alleles enriched in FinnsSemantic proximity Read

Copy number variant association analysis in 94,730 Chinese adults reveals loci influencing anthropometric and cardiometabolic traitsSemantic proximity Read

Long read sequencing of 3,622 Icelanders provides insight into the role of structural variants in human diseases and other traitsSemantic proximity Read

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestriesSemantic proximity Read

Genome-wide scan and fine-mapping of rare nonsynonymous associations implicates intracellular lipolysis genes in fat distribution and cardio-metabolic riskSemantic proximity Read

The biomedical landscape of genomic structural variation in the qatari population.Semantic proximity Read

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.Semantic proximity Read