Association of structural variation with cardiometabolic traits in Finns.

doi:10.1016/j.ajhg.2021.03.008

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Article

Association of structural variation with cardiometabolic traits in Finns.

American journal of human genetics - 1 Apr 2021

Chen Lei, Abel Haley J, Das Indraniel, Larson David E, Ganel Liron, Kanchi Krishna L, Regier Allison A, Young Erica P, Kang Chul Joo, Scott Alexandra J, Chiang Colby, Wang Xinxin, Lu Shuangjia, Christ Ryan, Service Susan K, Chiang Charleston W K, Havulinna Aki S, Kuusisto Johanna, Boehnke Michael, Laakso Markku, Palotie Aarno, Ripatti Samuli, Freimer Nelson B, Locke Adam E, Stitziel Nathan O, Hall Ira M

Abstract excerpt

The contribution of genome structural variation (SV) to quantitative traits associated with cardiometabolic diseases remains largely unknown. Here, we present the results of a study examining genetic association between SVs and cardiometabolic traits in the Finnish population. We used sensitive methods to identify and genotype 129,166 high-confidence SVs from deep whole-genome sequencing (WGS) data of 4,848...

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Identifiers

PMID: 33798444
DOI: 10.1016/j.ajhg.2021.03.008
PMCID: PMC8059371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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