Article

Exome sequencing identifies high-impact trait-associated alleles enriched in Finns

2018-11-07

Abstract excerpt

<h4>ABSTRACT</h4> As yet undiscovered rare variants are hypothesized to substantially influence an individual’s risk for common diseases and traits, but sequencing studies aiming to identify such variants have generally been underpowered. In isolated populations that have expanded rapidly after a population bottleneck, deleterious alleles that passed through the bottleneck may be maintained at much higher frequen...

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Literature Corpus work: b12b5f36-b81b-5fc2-9e21-4fbab20fe449
DOI: 10.1101/464255

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