Article

Role of H2AX and p53 in Various Grades of Oral Submucous Fibrosis (OSF) in Malignant Transformation: A Cross-sectional study

2026-08-31

Abstract excerpt

<title>Abstract</title> <p>Background Oral submucous fibrosis (OSF) is a potentially malignant disorder of the oral cavity, strongly associated with areca nut and tobacco use. This fact is proven; that this chronic disorder carries a risk of transformation into oral squamous cell carcinoma (OSCC). Malignant transformation is preceded by DNA damage and dysregulation of the DNA damage response (DDR) molecules, whi...

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Literature Corpus work: c7fcfdec-130f-53b7-98e9-ddd7eac19f6f
DOI: 10.21203/rs.3.rs-10401060/v1

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