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Article

Correlation of epigenetic change and identification of risk factors for oral submucous fibrosis.

The International journal of biological markers - 27 Dec 2012

Xu Chunjiao, Zhao Jing, Loo Wings T Y, Hao Liang, Wang Min, Cheung Mary N B, Dou Yiding, Yip Adrian Y S, Ng Elizabeth L Y, Chow Louis W C, Liu Qing

Abstract excerpt

BACKGROUND: DNA methylation of certain genes is an epigenetic change that is essential for tumorigenesis. Oral submucous fibrosis (OSF) is a precancerous condition of oral mucosa with inflammation and progressive fibrosis of the lamina propria and deeper connective tissue. The hypermethylation of E-cadherin and cyclooxygenase 2 (COX-2) in chronic inflammation may demonstrate a mild lesion/mutation at epigenetic...

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Source

Identifiers

PMID: 23250779
DOI: 10.5301/JBM.2012.9937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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