Back to search

Article

Sperm specific expression of temperature-sensitive ion channel TRPM8 correlates with vertebrate evolution

2014-07-21

Abstract excerpt

Transient Receptor Potential subfamily Melastatin member 8 (TRPM8) is involved in detection of cold temperature and different noxious compounds, execute thermo- as well as chemo-sensitive responses at cellular levels. Here we explored the molecular evolution of TRPM8 by analyzing sequences from different species. We elucidate that different regions of TRPM8 had different levels of selection pressure and the 4-5 t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c7d59acd-5762-5ed7-8502-bb1a3d48de6b
DOI
10.7287/peerj.preprints.440v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Sperm specific expression of temperature-sensitive ion channel TRPM8 correlates with vertebrate evolutionDOI 10.7287/peerj.preprints.440v1
TRPM8.Semantic proximity
Melastatin subfamily Transient Receptor Potential channels support spermatogenesis in planarian flatwormsSemantic proximity
TRPV4 is the temperature-sensitive ion channel of human spermSemantic proximity
Thermal Adaptations in Animals: Genes, Development, and Evolution.Semantic proximity
Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and InvasionSemantic proximity
Why individual thermo sensation and pain perception varies? Clue of disruptive mutations in TRPVs from 2504 human genome data.Semantic proximity
TRPM4.Semantic proximity
The transient receptor potential family of ion channels.Semantic proximity
Role of TRPV4 in skeletal function and its mutant-mediated skeletal disorders.Semantic proximity
TRPM7.Semantic proximity
TRPV4-pathy, a novel channelopathy affecting diverse systems.Semantic proximity
Human local adaptation of the TRPM8 cold receptor along a latitudinal clineSemantic proximity
Select a neighboring publication to make it the new centre.