Article

Predicting disease-overarching therapeutic approaches for Congenital Disorders of Glycosylation using multi-OMICS

2025-07-10

Abstract excerpt

<h4>Background</h4> Congenital Disorders of Glycosylation (CDG) are a rapidly expanding group of inherited metabolic diseases caused by defects in glycosylation. Although over 190 genetic defects have been identified, effective treatments remain available for only a few. We hypothesized that integrative analysis of multi-omics datasets from individuals with various CDG could uncover common molecular signatures an...

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Literature Corpus work: a78e1ba8-18bc-5c90-8dd5-8be34f05e0d6
DOI: 10.1101/2025.07.07.663468

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